thanks nina! yes, i started on manual drain, as well. i was switched to the cycler shortly thereafter and find it the best, so far. but, as i mentioned, the cycler moves the fluid through the stomach 6 times per night, whereas the manual method does it four times, per day. my concern is that the more in and out, through the stomach lining, the more the wear and tear on the stomach lining, which means that one's ability to perform peritoneal dialysis may be shortened somewhat, by the cycler method.no?love~LL~