I skip every week on a Saturday night and also I have just finished a four day vacation and I didn't dialyse at all and had no ill effects. I don't retain fluid and my haemoglobin and potassium levels are normal so I don't get any physical symptoms. I have argued with my clinic that I should still be pre-dialysis but they say not. So I put my faith in our medical system and continue on nightly PD. But I'm dammed if I'm going to mess about dialysing while on vacation. I've not told my clinic that I do this but if they do find out they can like it or lump it.