From Medscape Nephrology > Berns on Nephrology
Higher Mortality Rates in For-Profit Dialysis Centers: Is it True?
Jeffrey S. Berns, MD LISTEN TO AUDIO:
http://www.medscape.com/viewarticle/735200Authors and Disclosures
Posted: 01/12/2011
Hello, this is Jeffrey Berns from the University of Pennsylvania School of Medicine in Philadelphia. I'm Editor-in-Chief of Medscape Nephrology. I recently came across a paper that was published in a journal called Health Services Research,[1] which looked at mortality outcomes in patients in for-profit compared with not-for-profit dialysis facilities, in a period of time between 2004 and 2006.
This particular study looked at 4 for-profit chains, which were not identified in the paper, but during the period the study dialyzed between 3400 and more than 10,000 patients. These 4 chains were compared with 1 not-for-profit chain, which dialyzed about 1400 patients, and then there were 2 collections (which were not very well described in the paper) of nonchain units that were for profit, and not for profit, that dialyzed smaller numbers of patients.
Before going any further, I should provide a disclaimer that the dialysis units affiliated with the University of Pennsylvania in which our faculty sees patients are owned by a large for-profit dialysis facility.
The findings of the study, which I should note, included patients who were a mix of prevalent and incident, although mostly prevalent, they had to have survived at least 90 days on dialysis, and the mix of prevalent and incident patients was not clear. They excluded patients with HIV infection.
The study period was 2004 to 2006, with a mean follow-up of 16 months. In their unadjusted analysis, mortality was 4%-21% higher in the various dialysis units compared with the reference group, which was the not-for-profit chain. In an adjusted analysis, 6%-24% higher mortality was observed. These differences for the most were either not statistically significant or of borderline statistical significance.
As you can imagine, the patient characteristics were hugely different in many respects across these different facilities, sometimes in favor of the for-profit facilities, sometimes in favor of the not-for-profit facilities, and it's very hard to sort out what differences between the patient populations and facilities might explain these findings. Previous literature in this area, clearly has identified, differences in patterns of treatment in dialysis facilities. One study, for instance, showed higher erythropoiesis-stimulating agent use, but also higher hemoglobin levels, T stats, and urea reduction ratios, but no differences in mortality. Other studies, with 1 exception, have not found differences in mortality.
The interesting question in my mind is, why, and is this real? Is it a patient characteristic issue? Is it a dialysis facility issue? Is it even a real observation? When one applies a variety of statistical techniques to try to correct for what are very different demographic and clinical features among patients at dialysis facilities of different sizes and different geographic locations, it's very difficult to tease out whether there really is a meaningful or significant and important mortality difference between for-profit and not-for-profit facilities.
This is obviously very important, given the increasing trend towards large chains that are for-profit, so it's an interesting study. It's retrospective; it's observational, and it's provocative. It requires further study to better understand whether this is a real observation and the implications for it. It would be an interesting study to compare what happens to patient outcomes in a particular facility that converts from not-for-profit with for-profit or in the other direction, although I'm not sure that many facilities could be studied with that kind of format, but it would be interesting.
If you have any particular comments about this, please submit them through the Medscape Webpage. I hope everyone had a happy holiday. Take care now. This is Jeff Berns from the University of Pennsylvania School of Medicine in Philadelphia.