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Author Topic: Elevated Liver Enzymes In My Puppy.  (Read 16801 times)
Rerun
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« on: March 22, 2010, 09:09:38 PM »

I took Tia to the vet today to be spayed.  Two hours later they called me and said they could not do the surgery because her liver enzymes were elevated.  He said we would put her on antibiotics (2 weeks) and then do blood work again.  If they are still elevated he suspects a Liver Shunt and we could do an ultrasound to see.  A liver shunt is where their circulatory system bypasses the liver and the toxins don't get processes.  One of the symptoms is vomiting and I've seen her do it yesterday and today.  There is a surgery but it is not always successful and the prognosis is "guarded".    I'm hoping it is an infection and the next blood work is perfect??

She will be 9 months old April 3. 

           :(
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monrein
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« Reply #1 on: March 23, 2010, 07:23:00 AM »

Sorry to hear this about Tia.  I copied and sent your message to my brother (he's a veterinary surgeon) to see if he had any comments or suggestions about her situation.  I'll let you know what I find out.   :grouphug;
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Pyelonephritis (began at 8 mos old)
Home haemo 1980-1985 (self-cannulated with 15 gauge sharps)
Cadaveric transplant 1985
New upper-arm fistula April 2008
Uldall-Cook catheter inserted May 2008
Haemo-dialysis, self care unit June 2008
(2 1/2 hours X 5 weekly)
Self-cannulated, 15 gauge blunts, buttonholes.
Living donor transplant (sister-in law Kathy) Feb. 2009
First failed kidney transplant removed Apr.  2009
Second trx doing great so far...all lab values in normal ranges
Rerun
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« Reply #2 on: March 23, 2010, 02:27:28 PM »

Sorry to hear this about Tia.  I copied and sent your message to my brother (he's a veterinary surgeon) to see if he had any comments or suggestions about her situation.  I'll let you know what I find out.   :grouphug;

WOW!  That is great!  Thanks~       :-*
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Deanne
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« Reply #3 on: March 23, 2010, 02:52:20 PM »

One of my dogs was suspected of having a liver shunt and was tested for it. It's been a few years, so my memory might be faulty. There are two different types of liver shunts -- small and large (or some such thing). I think with a large shunt (fixable by surgery), the blood vessels on the outside of the liver are at fault and with a small shunt, it's the blood vessels within the liver (worse prognosis). Tigger didn't have an ultrasound though. There's a specific test they can do where they run a blood test after a 12-hour fast, then feed the dog and test again to compare the results.

I hope your pup is OK!
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Deanne

1972: Diagnosed with "chronic kidney disease" (no specific diagnosis)
1994: Diagnosed with FSGS
September 2011: On transplant list with 15 - 20% function
September 2013: ~7% function. Started PD dialysis
February 11, 2014: Transplant from deceased donor. Creatinine 0.57 on 2/13/2014
monrein
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« Reply #4 on: March 23, 2010, 05:33:06 PM »

Right on the money there Deanne. 

Rerun, my brother says that elevated liver enzymes could be the result of a shunt but that he wouldn't go immediately to that possibility.  The test Deanne refers to is a fasting bioacids test which can yield more information and isn't invasive.  He also said that there are several different types of shunts and prognosis depends on location (intra-hepatic or extra-hepatic) and also depends on how many blood vessels are involved.  Some are treated relatively easily and the dog can return to normal after surgery, while others are just too complex to tackle.
He said that a dog's behaviour can be a good indication if it is a shunt, especially if after a high protein meal the pup goes nuts, totally out of character, turning into a little Tasmanian devil.  They can sometimes display neurological type symptoms, leaning up against a wall for example.

Jim said that elevated liver enzymes can also be due to something as simple as a dog eating a tylenol or getting into chocolate or something they shouldn't eat.
A final point is that, in the case of a shunt,  prognosis is improved if things are detected early on and corrected.  If things are undetected for a long time the liver will atrophy and become small and cirrohotic and the blood vessels will have enlarged.

Hope this helps and that Tia will NOT have a shunt.  Poor little pup. 

This is very much a paraphrase of Jim's long detailed talk with me a few minutes ago but he did say that it seems a little premature to think it's a shunt just yet.   :cuddle;
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Pyelonephritis (began at 8 mos old)
Home haemo 1980-1985 (self-cannulated with 15 gauge sharps)
Cadaveric transplant 1985
New upper-arm fistula April 2008
Uldall-Cook catheter inserted May 2008
Haemo-dialysis, self care unit June 2008
(2 1/2 hours X 5 weekly)
Self-cannulated, 15 gauge blunts, buttonholes.
Living donor transplant (sister-in law Kathy) Feb. 2009
First failed kidney transplant removed Apr.  2009
Second trx doing great so far...all lab values in normal ranges
paris
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« Reply #5 on: March 23, 2010, 06:07:51 PM »

Monrein, that was very nice of you to go the extra mile and find out information for Rerun.  Your brother is just as kind for giving his advice.  You just have to love IHD family.   :cuddle;
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It's not what you gather, but what you scatter that tells what kind of life you have lived.
sullidog
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« Reply #6 on: March 24, 2010, 05:42:07 PM »

I hope all is well with your pup, keep us posted!
Troy
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May 13, 2009, went to urgent care with shortness of breath
May 19, 2009, went to doctor for severe nausea
May 20, 2009, admited to hospital for kidney failure
May 20, 2009, started dialysis with a groin cath
May 25, 2009, permacath was placed
august 24, 2009, was suppose to have access placement but instead was admited to hospital for low potassium
august 25, 2009, access placement
January 16, 2010 thrombectomy was done on access
Rerun
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« Reply #7 on: March 24, 2010, 06:04:25 PM »

Thanks a million Monrein and tell your brother thanks too.

She's scheduled for an ultrasound on Friday.  I can't wait for the two weeks of antibiotics like my vet originally suggested kind of a wait and see.  I've seen her vomit 3 times and so I just have to know.  I stopped to see my vet today and he started out by saying "We are not sure it is a shunt, we like to start with the least expensive tests first".  My thought is lets cut to the chase.  If an ultrasound can detect it than lets do it. 

I read about the 12 hour fast and then feed and then blood test also.  I'll mention that to him.  Thanks.

I got home after dialysis this morning at 4:15 and fed her and about a half hour later she vomited and then ate it so I'm not sure what is going on. 

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okarol
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« Reply #8 on: March 24, 2010, 06:18:32 PM »

 :cuddle; I hope she's ok Rerun.
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Admin for IHateDialysis 2008 - 2014, retired.
Jenna is our daughter, bad bladder damaged her kidneys.
Was on in-center hemodialysis 2003-2007.
7 yr transplant lost due to rejection.
She did PD Sept. 2013 - July 2017
Found a swap living donor using social media, friends, family.
New kidney in a paired donation swap July 26, 2017.
Her story ---> https://www.facebook.com/WantedKidneyDonor
Please watch her video: http://youtu.be/D9ZuVJ_s80Y
Living Donors Rock! http://www.livingdonorsonline.org -
News video: http://www.youtube.com/watch?v=J-7KvgQDWpU
Jean
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« Reply #9 on: March 24, 2010, 07:12:20 PM »

 Sorry Rerun, I hope she is okay too.
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paris
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« Reply #10 on: March 25, 2010, 06:33:15 PM »

How is little Tia today?  Hope you get some answers soon.
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It's not what you gather, but what you scatter that tells what kind of life you have lived.
Rerun
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Going through life tied to a chair!

« Reply #11 on: March 26, 2010, 06:24:01 PM »

Good News!!   :cheer:

The ultrasound showed a normal liver!  I feel bad for over reacting.  She got her belly shaved and she is groggy.  They had to sedate her a little because she was squirmy.  Poor baby.  I've given her bits of food and some rice milk.  I'm going to let her sleep.  Pebbles is sleeping by her.

Thank God!  I was worried.             :pray;
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jbeany
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« Reply #12 on: March 26, 2010, 07:05:12 PM »

 :bandance;
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paris
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« Reply #13 on: March 26, 2010, 08:38:56 PM »

Thank goodness!  Let sweet Tia rest and recover.  Give her hugs from all of us.   :cuddle;
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It's not what you gather, but what you scatter that tells what kind of life you have lived.
monrein
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« Reply #14 on: March 26, 2010, 09:23:40 PM »

Good News!!   :cheer:

The ultrasound showed a normal liver!  I feel bad for over reacting.  She got her belly shaved and she is groggy.  They had to sedate her a little because she was squirmy.  Poor baby.  I've given her bits of food and some rice milk.  I'm going to let her sleep.  Pebbles is sleeping by her.

Thank God!  I was worried.             :pray;

You must be so relieved.  I'm happy to hear the news and I'll let Jim know too. 
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Pyelonephritis (began at 8 mos old)
Home haemo 1980-1985 (self-cannulated with 15 gauge sharps)
Cadaveric transplant 1985
New upper-arm fistula April 2008
Uldall-Cook catheter inserted May 2008
Haemo-dialysis, self care unit June 2008
(2 1/2 hours X 5 weekly)
Self-cannulated, 15 gauge blunts, buttonholes.
Living donor transplant (sister-in law Kathy) Feb. 2009
First failed kidney transplant removed Apr.  2009
Second trx doing great so far...all lab values in normal ranges
Mimi
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« Reply #15 on: March 26, 2010, 11:46:36 PM »

Hooray.....Tia is OK.
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Rerun
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Going through life tied to a chair!

« Reply #16 on: March 27, 2010, 07:53:01 AM »

Thanks everyone and especially JIM our IHD vet.

                     :flower;
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okarol
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« Reply #17 on: March 27, 2010, 10:51:19 AM »

 :cuddle; Great, hope she feels better. So do they know why the numbers were elevated?
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Admin for IHateDialysis 2008 - 2014, retired.
Jenna is our daughter, bad bladder damaged her kidneys.
Was on in-center hemodialysis 2003-2007.
7 yr transplant lost due to rejection.
She did PD Sept. 2013 - July 2017
Found a swap living donor using social media, friends, family.
New kidney in a paired donation swap July 26, 2017.
Her story ---> https://www.facebook.com/WantedKidneyDonor
Please watch her video: http://youtu.be/D9ZuVJ_s80Y
Living Donors Rock! http://www.livingdonorsonline.org -
News video: http://www.youtube.com/watch?v=J-7KvgQDWpU
Rerun
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Going through life tied to a chair!

« Reply #18 on: March 28, 2010, 11:23:07 AM »

:cuddle; Great, hope she feels better. So do they know why the numbers were elevated?

No.  She will finish her antibiotics.  I may have just been an infection of some kind.
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Darthvadar
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« Reply #19 on: March 28, 2010, 03:03:16 PM »

Great news....

It's always a worry when our pawed people are sick....

Darth...
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Cared for my late mum, Elsie who had Kidney Failure... Darling mum died on July 15th 2014... May her gentle soul rest in peace....
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