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Author Topic: Calcitriol versus Paricalcitol for Vitamin D deficiency  (Read 12756 times)
kamalshah20
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« on: November 20, 2009, 06:40:08 PM »

I was put on Calcitriol 0.25 mcg per day a couple of days back to treat my Vit D deficiency. I have had a high PTH for months now and I am on Cinacalcet for that.

I was looking up Calcitriol on the internet and I found two bits of information - one which said that calcitriol is contraindicated in treating Vit D deficiency (http://www.vitamindcouncil.org/treatment.shtml) and one more that said that paricalcitol (Zemplar) was better than calcitriol (http://content.nejm.org/cgi/content/full/349/5/496) in terms of causing hypercalcemia. I'm wondering then about why I was put on calcitriol as opposed to paricalcitol?

Any thoughts?

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Kamal
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Zach
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« Reply #1 on: November 20, 2009, 07:59:06 PM »

I'm on IV Zamplar after each treatment, and it works to some degree without raising calcium too much.
Calcitriol, I believe, is an older medicine and thus less expensive, especially if it's in the oral form.

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Uninterrupted in-center (self-care) hemodialysis since 1982 -- 34 YEARS on March 3, 2016 !!
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Marsh
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« Reply #2 on: November 22, 2009, 05:41:33 PM »

I'm on Zemplar and it is very expensive ($360/month), and my insurance doesn't cover it.  But, the drug company has a program where I only have to pay 20%.  So, that helps a lot.
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kamalshah20
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« Reply #3 on: November 22, 2009, 05:55:32 PM »

Ok. Thanks Zach and Marsh for your replies.

One thing I found is that Calcitriol causes an increase in phosphorus apart from an increase in Calcium. I've been struggling  with a low phosphorus ever since I started nocturnal dialysis. So, maybe, it might be good to take Calcitriol.

Thanks
Kamal
http://kamaldshah.com
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Zach
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« Reply #4 on: November 22, 2009, 06:22:46 PM »


I've been struggling  with a low phosphorus ever since I started nocturnal dialysis. So, maybe, it might be good to take Calcitriol.


Either that or an ice cream sundae each night before dialysis.    :rofl;
« Last Edit: November 22, 2009, 06:39:50 PM by Zach » Logged

Uninterrupted in-center (self-care) hemodialysis since 1982 -- 34 YEARS on March 3, 2016 !!
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
No transplant.  Not yet, anyway.  Only decided to be listed on 11/9/06. Inactive at the moment.  ;)
I make films.

Just the facts: 70.0 kgs. (about 154 lbs.)
Treatment: Tue-Thur-Sat   5.5 hours, 2x/wk, 6 hours, 1x/wk
Dialysate flow (Qd)=600;  Blood pump speed(Qb)=315
Fresenius Optiflux-180 filter--without reuse
Fresenius 2008T dialysis machine
My KDOQI Nutrition (+/ -):  2,450 Calories, 84 grams Protein/day.

"Living a life, not an apology."
kamalshah20
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« Reply #5 on: November 22, 2009, 06:35:28 PM »

Or a glass full of cola perhaps! ;D
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del
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« Reply #6 on: December 13, 2009, 11:19:01 AM »

Nocturnal dialysis will help lower you phosphorus. My husband has to make sure he eats lots of high phos food since starting nocturnal.  He just finished a glas of cola!!
What a difference from conventional when he had to almost eliminate high phos foods plus take binders!! He takes rocaltrol for vitamin D and to lower PTH.  He takes 0.25 one day and 0.5 the next day.  His PTH has dropped a lot since starting nocturnal.  He does 5 nights a week on home nocturnal for 7 or 8 hrs a night.
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HubbysPartner
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« Reply #7 on: December 14, 2009, 09:52:54 AM »

My husband takes calcitriol orally once a day and has zemplar given three times a week during treatment.  His phosphorus and calcium levels are good as well as his PTH.  He doesn't have to worry too much about high phosphorus foods and only needs to take a binder if his meal is really high in phosphorus.  I'm hoping things continue that way.
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Charlie B53
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« Reply #8 on: December 24, 2015, 06:58:47 AM »


Reported ad posting to Mod.
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SooMK
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« Reply #9 on: December 24, 2015, 03:20:35 PM »

Thanks Charlie. I was too quick and reported it again before seeing your post.
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SooMK
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