Kidney International advance online publication
20 May 2009; doi: 10.1038/ki.2009.156
Cognitive–behavioral group therapy is an effective treatment for major depression in hemodialysis patientsPriscila Silveira Duarte1, Maria Cristina Miyazaki2, Sergio Luís Blay3 and Ricardo Sesso1
1Department of Medicine, Division of Nephrology, Federal University of Săo Paulo, Sao Paulo, Brazil
2School of Medicine of Săo José do Rio Preto, Sao Paulo, Brazil
3Department of Psychiatry, Federal University of Săo Paulo, Sao Paulo, Brazil
Correspondence: Priscila Silveira Duarte, Rua Benjamin Constant, 4372, apto.121, Imperial, Săo José do Rio Preto, Săo Paulo 15015-600, Brazil. E-mail: psduarte@nefro.epm.br
Received 8 October 2008; Revised 27 March 2009; Accepted 1 April 2009; Published online 20 May 2009.
Top of pageAbstract
Depression is an important target of psychological assessment in patients with end-stage renal disease because it predicts their morbidity, mortality, and quality of life. We assessed the effectiveness of cognitive–behavioral therapy in chronic hemodialysis patients diagnosed with major depression by the Mini International Neuropsychiatric Interview (MINI). In a randomized trial conducted in Brazil, an intervention group of 41 patients was given 12 weekly sessions of cognitive–behavioral group therapy led by a trained psychologist over 3 months while a control group of 44 patients received the usual treatment offered in the dialysis unit. In both groups, the Beck Depression Inventory, the MINI, and the Kidney Disease and Quality of Life-Short Form questionnaires were administered at baseline, after 3 months of intervention or usual treatment, and after 9 months of follow-up. The intervention group had significant improvements, compared to the control group, in the average scores of the Beck Depression Inventory overall scale, MINI scores, and in quality-of-life dimensions that included the burden of renal disease, sleep, quality of social interaction, overall health, and the mental component summary. We conclude that cognitive–behavioral group therapy is an effective treatment of depression in chronic hemodialysis patients.
Keywords: cognitive-behavioral therapy, depression, end-stage renal disease, hemodialysis, quality of life
http://www.nature.com/ki/journal/vaop/ncurrent/abs/ki2009156a.html