Vit D and Kidney Disease

Interesting findings for those pre dialysis patients.

Vitamin D Curbs Albuminuria in Kidney Disease
Sep 11, 2013

NEW YORK (Reuters Health) Sep 11 - Vitamin D supplementation decreases albuminuria and might slow the progression of chronic kidney disease (CKD), according to Spanish researchers.

"The study suggests that vitamin D repletion with daily mild doses of cholecalciferol may be effective to reduce albuminuria in patients with CKD 3-4 stage, with potential long-term benefits for this population," Dr. Pablo Molina told Reuters Health by email. "In addition, we observed a modest but significant decline in PTH (parathyroid hormone) levels after cholecalciferol administration."

In a report online August 24 in Nephrology Dialysis Transplantation, Dr. Molina of Hospital Universitario Dr Peset, Valencia, and colleagues note that several observational studies suggest that vitamin D deficiency is related to albuminuria and other untoward effects. There is growing evidence that vitamin D receptor activation may have antiproteinuric effects.

To investigate further, the researchers prospectively studied 101 CKD patients. None were on dialysis and all had albuminuria