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Author Topic: Wearable Dialysis: Toward a 2-Pound Artificial Kidney  (Read 3552 times)
okarol
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Photo is Jenna - after Disneyland - 1988

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« on: October 23, 2009, 10:47:19 AM »


Wearable Dialysis: Toward a 2-Pound Artificial Kidney


Fri Oct 23, 2009 10:27am EDT
 
LOS ANGELES, Oct. 23, 2009 (GLOBE NEWSWIRE) -- AWAK Technologies, Inc. is
unveiling its peritoneal dialysis-based wearable artificial kidney, envisioned
to weigh 2 pounds, during its debut presentation at the American Society of
Nephrology (ASN) - Renal Week, held at the San Diego Convention Center from
29-31st October 2009.

Currently, AWAK (Automated Wearable Artificial Kidney) is a 6-pound
battery-operated prototype designed to provide 24/7 continuous dialysis.
However, through continuous developmental effort, AWAK is working toward a
weight of merely 2 pounds. This technological breakthrough is based on original
joint research with the University of California, Los Angeles (UCLA) and the
Department of Veterans Affairs, USA.

"It is truly a disruptive innovation that will change the landscape of the
dialysis industry," said Dr. Gordon Ku, Chairman of AWAK Technologies. "Besides
improving the quality of life for patients, the paradigm changes from
'facilities-based dialysis' to 'personal-based dialysis,' this is vital in
lowering the cost of the national healthcare system. More importantly, it
contributes to the economy by allowing patients to be economically productive."

"Freedom is the keyword," commented Dr. Martin Roberts, Chief Scientist &
Inventor. "AWAK returns the lifestyles back to the patients: to work, to travel
and to play. Patients are now freed from dialytic regimes, freed from stringent
dietary and fluid constraints, and freed from being bounded to a geographical
locality."

Dr. David B. N. Lee, Chief Scientist and inventor, said, "Based on the technique
of peritoneal dialysis (PD) and sorbent-based regeneration of used dialysate in
perpetuity, AWAK is both 'bloodless' and 'waterless.' Round-the-clock dialysis
and ultra-filtration represents the ultimate form of 'frequent dialysis' and is
expected to provide steady-state metabolic and fluid regulation. Because both
the aqueous and the protein components of the used dialysate are regenerated and
recycled, AWAK produces a novel protein-containing dialysate that is expected to
reduce or eliminate protein-loss, with the additional possibility of removing
protein-bound toxins."

The first prototype is designed to provide a net dialysate exchange rate of 4 L
per hour. Based on a recent completed study on 8 patients using tidal peritoneal
dialysis (reserve volume 500 ml, tidal volume 250 ml), this flow rate will
translate into a weekly Kt/V of 4, a 100% increase over that used in current
practice. AWAK will also incorporate a number of components focused on reducing
infectious complications. The device is in the process of procuring FDA
certification and is planned for clinical trials in the United States and
Singapore in 2010.

About AWAK Technologies

AWAK Technologies was incorporated in April 2007 with the mission of Saving,
Sustaining & Enhancing Lives of End-Stage Renal Disease (ESRD) patients. AWAK,
The Wearable Dialysis Company dedicated to the development of wearable
artificial kidneys, was founded by Dr. Gordon Ku (Chairman of Kidney Dialysis
Foundation), Dr. David B. N. Lee and Dr. Martin Roberts (both of the United
States Department of Veterans Affairs Healthcare System and David Geffen School
of Medicine at UCLA), and Mr. Neo Kok Beng. Dr. David B. N. Lee and Dr. Martin
Roberts are also inventors of the licensed technologies and serve as Chief
Scientists in the Company.

The AWAK Technologies, Inc. logo is available at
http://www.globenewswire.com/newsroom/prs/?pkgid=6752

-0-
CONTACT:  AWAK Technologies, Inc.
          Media Contact:
          Clarissa Khoo
          clarissa@awak.com
          www.awak.com

http://www.reuters.com/article/pressRelease/idUS152005%2B23-Oct-2009%2BGNW20091023
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Admin for IHateDialysis 2008 - 2014, retired.
Jenna is our daughter, bad bladder damaged her kidneys.
Was on in-center hemodialysis 2003-2007.
7 yr transplant lost due to rejection.
She did PD Sept. 2013 - July 2017
Found a swap living donor using social media, friends, family.
New kidney in a paired donation swap July 26, 2017.
Her story ---> https://www.facebook.com/WantedKidneyDonor
Please watch her video: http://youtu.be/D9ZuVJ_s80Y
Living Donors Rock! http://www.livingdonorsonline.org -
News video: http://www.youtube.com/watch?v=J-7KvgQDWpU
Brightsky69
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« Reply #1 on: October 23, 2009, 12:05:41 PM »

Where do i sign up?   :2thumbsup;
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Transplant June 11, 1991 (1st time) my mom's kidney
Received my 2nd kidney transplant Oct. 19th 2010.
RightSide
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« Reply #2 on: October 23, 2009, 05:05:06 PM »

when they get it down to 2 pounds,
I may well go for it!
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Zach
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"Still crazy after all these years."

« Reply #3 on: October 23, 2009, 05:11:38 PM »

Sounds like the purpose of this press release is to find additional investors.

8)
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Uninterrupted in-center (self-care) hemodialysis since 1982 -- 34 YEARS on March 3, 2016 !!
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
No transplant.  Not yet, anyway.  Only decided to be listed on 11/9/06. Inactive at the moment.  ;)
I make films.

Just the facts: 70.0 kgs. (about 154 lbs.)
Treatment: Tue-Thur-Sat   5.5 hours, 2x/wk, 6 hours, 1x/wk
Dialysate flow (Qd)=600;  Blood pump speed(Qb)=315
Fresenius Optiflux-180 filter--without reuse
Fresenius 2008T dialysis machine
My KDOQI Nutrition (+/ -):  2,450 Calories, 84 grams Protein/day.

"Living a life, not an apology."
okarol
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Photo is Jenna - after Disneyland - 1988

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« Reply #4 on: October 23, 2009, 05:14:46 PM »


I really am tempted to drive down to that conference next week and see if they've got anything to show or if it's all still on paper.
Logged


Admin for IHateDialysis 2008 - 2014, retired.
Jenna is our daughter, bad bladder damaged her kidneys.
Was on in-center hemodialysis 2003-2007.
7 yr transplant lost due to rejection.
She did PD Sept. 2013 - July 2017
Found a swap living donor using social media, friends, family.
New kidney in a paired donation swap July 26, 2017.
Her story ---> https://www.facebook.com/WantedKidneyDonor
Please watch her video: http://youtu.be/D9ZuVJ_s80Y
Living Donors Rock! http://www.livingdonorsonline.org -
News video: http://www.youtube.com/watch?v=J-7KvgQDWpU
Zach
Elite Member
*****
Offline Offline

Gender: Male
Posts: 4820


"Still crazy after all these years."

« Reply #5 on: October 23, 2009, 05:20:57 PM »


I really am tempted to drive down to that conference next week and see if they've got anything to show or if it's all still on paper.

 :beer1;
Logged

Uninterrupted in-center (self-care) hemodialysis since 1982 -- 34 YEARS on March 3, 2016 !!
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
No transplant.  Not yet, anyway.  Only decided to be listed on 11/9/06. Inactive at the moment.  ;)
I make films.

Just the facts: 70.0 kgs. (about 154 lbs.)
Treatment: Tue-Thur-Sat   5.5 hours, 2x/wk, 6 hours, 1x/wk
Dialysate flow (Qd)=600;  Blood pump speed(Qb)=315
Fresenius Optiflux-180 filter--without reuse
Fresenius 2008T dialysis machine
My KDOQI Nutrition (+/ -):  2,450 Calories, 84 grams Protein/day.

"Living a life, not an apology."
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