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Dialysis Discussion => Dialysis: F.A.Q. (Frequently Asked Questions) => Topic started by: Stoday on March 23, 2010, 07:38:10 PM

Title: No longer a need for parathyroidectomy?
Post by: Stoday on March 23, 2010, 07:38:10 PM
My PTH has risen to over 200 pg/ml. Neph has prescribed Cinacalcet, which, he says, should eliminate the need for parathyroidectomy surgery. I've not heard of this drug before. Anyone else taking it?
Title: Re: No longer a need for parathyroidectomy?
Post by: cloud393 on March 24, 2010, 10:57:25 AM
I haven't heard of that one.  Sorry.  I get Zemplar. 
Title: Re: No longer a need for parathyroidectomy?
Post by: jbeany on March 24, 2010, 11:04:42 AM
In theory, there are a group of drugs that can lower the PTH and prevent surgery.  It's all mostly a synthetic Vit. D, I think.  In reality, the drugs won't work for everyone, or won't work well enough, and sometimes the only cure is surgery. 

I haven't heard of that one, either.  I was on Hectorol, after the Sensipar started making me vomit.
Title: Re: No longer a need for parathyroidectomy?
Post by: sullidog on March 24, 2010, 05:28:12 PM
Never heard of it, I'm only on zemplar since that seems to be the only PTH med my body can handle.
Troy
Title: Re: No longer a need for parathyroidectomy?
Post by: -Lady Noir- on March 25, 2010, 01:53:38 AM
Hmm, they tried to lower Mikes PTH for months,[phosphate binders] to no avail. Possibly because it had been so high for so long before they did anything about it.

Fingers crossed this one works for you Stoday  ;D
Title: Re: No longer a need for parathyroidectomy?
Post by: Deanne on April 27, 2010, 01:14:09 PM
According to a web search Cinacalcet = Sensipar. Same medication, different name.
Title: Re: No longer a need for parathyroidectomy?
Post by: RichardMEL on April 28, 2010, 12:18:42 AM
yep, it's Sensipar. This drug has done wonders for me. My PTH was at 70 or so and they were talking about cutting my throat (parathyroidectomy)... bang on sensipar 4x/week 30mg and I'm down to 28-30 and doing fine. Can't speak more highly about this drug for me. I've had NO side effects, my calcium has lowered as well(which is what it does) and my Phos is also perfect.

I hope it helps lower yours!
Title: Re: No longer a need for parathyroidectomy?
Post by: galvo on April 28, 2010, 05:12:03 PM
I am confused, again. I can't find PTH on my path reports. What is it?
Title: Re: No longer a need for parathyroidectomy?
Post by: RichardMEL on April 28, 2010, 06:31:51 PM
I am confused, again. I can't find PTH on my path reports. What is it?

PTH measures your parathyroid hormone production. It's not a regular test that is run but is something your neph should definitely be keeping track of. Usually my unit does it every 3 months as a matter of course, but I usually get mine done more often. If you're concerned why not ask your neph or unit what your latest PTH was.

High PTH basically means that more Phos and Calcium are being sucked out of your bones, which down the track can lead to brittle bones, easy fratures, breaks etc.. and this is bad. So, to lower the PTH the usual course is either the operation to remove the parathyroid glands that up the PTH, or meds like Sensipar, which also lower it. Obviously taking a pill is a lot easier than having your throat cut :)
Title: Re: No longer a need for parathyroidectomy?
Post by: galvo on April 28, 2010, 08:47:47 PM
Oh! Will check this out. Thanks.
Title: Re: No longer a need for parathyroidectomy?
Post by: -Lady Noir- on April 29, 2010, 04:49:48 PM
I am confused, again. I can't find PTH on my path reports. What is it?

PTH measures your parathyroid hormone production. It's not a regular test that is run but is something your neph should definitely be keeping track of. Usually my unit does it every 3 months as a matter of course, but I usually get mine done more often. If you're concerned why not ask your neph or unit what your latest PTH was.

High PTH basically means that more Phos and Calcium are being sucked out of your bones, which down the track can lead to brittle bones, easy fratures, breaks etc.. and this is bad. So, to lower the PTH the usual course is either the operation to remove the parathyroid glands that up the PTH, or meds like Sensipar, which also lower it. Obviously taking a pill is a lot easier than having your throat cut :)

Amazing. Sensipar.. another drug i don't think we have over here!
The op was no walk in the park thats for sure!
Title: Re: No longer a need for parathyroidectomy?
Post by: RichardMEL on April 29, 2010, 08:24:28 PM
Sensipar was only approved for use in Oz maybe in 2007 or 2008. I know I had to wait quite awhile before it was generally approved for use, and before hand I got a few scripts under special medical approval(and all that stuff). Haven't looked back since I got on it though. They sometimes claim I am a bit of a model patient.....
Title: Re: No longer a need for parathyroidectomy?
Post by: -Lady Noir- on May 01, 2010, 02:30:23 PM
Oh i see! :)
When Mike chipped his hips, apparently his PTH was the highest they had ever seen.
Title: Re: No longer a need for parathyroidectomy?
Post by: Stoday on May 01, 2010, 07:21:12 PM
I got a telephone call last week to say to stop taking the Cinacalcet immeadiatly and take Phoslo instead. It turned out that my calcium level had dropped like a stone. Now I'm having weekly blood tests.

Maybe the Cinacalcet wasn't too good for me. I've not had a bad day since I've stopped taking it.