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Author Topic: Immunotherapy for cancer in renal transplant patients  (Read 122 times)
MooseMom
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« on: February 11, 2020, 08:42:36 AM »

I've been reading quite a bit in the past several years about the idea and the practice of immunotherapy in the treatment of various cancers.  Immunotherapy is the use of one's own immune system in the fight against malignancy.

In the current edition of Time magazine, a Nobel Prize winning immunologist from MD Anderson in Houston, Dr. James Allison, was interviewed.  He is best known for this :

https://en.wikipedia.org/wiki/Checkpoint_inhibitor

I have been wondering for a long time how immunotherapy would work in transplant patients, seeing as we are already "immunocompromised".  We all know that tx patients have a great risk for certain cancers, so I wondered if this avenue of treatment might be closed to us.  But then I found this:

https://www.sciencedaily.com/releases/2017/01/170118103829.htm

I just thuoght all of this was interesting and thought I'd share it with you all.
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"Eggs are so inadequate, don't you think?  I mean, they ought to be able to become anything, but instead you always get a chicken.  Or a duck.  Or whatever they're programmed to be.  You never get anything interesting, like regret, or the middle of last week."
SooMK
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« Reply #1 on: February 15, 2020, 08:27:14 AM »

Very interesting!
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SooMK
Diagnosed FJHN/UKD 2009
Transplant April 2014
cassandra
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When all else fails run in circles, shout loudly

« Reply #2 on: February 15, 2020, 10:41:08 AM »

Very interesting indeed, you would think it could be poss to determine which part of the immune system is responsible for a persons rejection of a transplanted organ, and target that part with checkpoint inhibitors too
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I started out with nothing and I still have most of it left

1983 high proteinloss in urine, chemo, stroke,coma, dialysis
1984 double nephrectomy
1985 transplant from dad
1998 lost dads kidney, start PD
2003 peritineum burst, back to hemo
2012 start Nxstage home hemo
       still on waitinglist, still ok I think
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