non-invasive test of immunosuppressive adequacy

[okarol]

I was wondering if anyone is familiar with TruGraf. Seems like a great alternative to kidney biopsies, which can be pretty scary for transplant patients, and they are not without risks. I just read about this and will check with Jenna's doctor at her next appointment. "TruGraf is the first non-invasive test of immunosuppressive adequacy" www.trugraf.com

[MooseMom]

I seem to remember answering a questionnaire on IHD about this, and I also seem to remember that the questionnaire led to a follow up telephone interview.  Does anyone else recall this?

[iolaire]

Sort of related I had the AlloSure test done to test for rejection instead of more biopsys.
http://www.allosure.com

AlloSure is the first and only non-invasive test that assesses organ health by directly measuring allograft injury. AlloSure can accurately determine active rejection, enabling better management of your kidney transplant patients.

[Cupcake]

I, too had the Allosure test a month after transplant and the result was zero so that's very good-none of my donor's DNA showed up in my blood-that's how it was explained to me. Plans are to do it quarterly, has to be drawn/sent to a lab in California. unfortunately my private insurance has already denied payment-the allosure website says medicare covers it so I am hopeful. Any experience from anyone else getting this covered?

[iolaire]

Plans are to do it quarterly, has to be drawn/sent to a lab in California.

They do not have a schedule for me (I’m at 1.5 years). I think they would do it only if something in the labs worry them. I have some low level inflammation in my blood and the biopsy didn’t show much so it was either another biopsy or the AlloSure test.

I guess to me quarterly sounds excessive unless there are concerns. Especially if it might not be covered by your insurance. I would not want to pay a grand every quarter out of pocket for the test.

My center does 6 and 12 month biopsy’s and then stops unless there are concerns from the labs.

[okarol]

Jenna finally got an Allosure test and it is fine. UCLA kept putting off the test because they said it's still in trials and people were getting false positives and it was causing unnecessary worry. But we told them we would be consignant of that and would retest if needed. There are a couple of other tests now, one mentioned here in this KidneyTalk podcast https://www.rsnhope.org/kidneytalk/assessing-your-kidney-transplant-health/

[MooseMom]

Please give Jenna our regards.  Thanks for the link; I will check it out!

Hope you are well, okarol!

[frugallyzing]

Jenna finally got an Allosure test and it is fine. UCLA kept putting off the test because they said it's still in trials and people were getting false positives and it was causing unnecessary worry. But we told them we would be consignant of that and would retest if needed. There are a couple of other tests now, one mentioned here in this KidneyTalk podcast https://www.rsnhope.org/kidneytalk/assessing-your-kidney-transplant-health/

That's great news. Thans for sharing the lnk