Introducing myself

[DrMoskowitz]

 

Hi,

I've been looking for a site like this for at least 9 years.

Fifteen years ago, I found out that too much ACE activity was behind most causes of kidney failure (1). So I used a higher-than-conventional dose of ACE inhibitor, and, voila!--I could reverse early stage kidney failure due to diabetes or high blood pressure (2). This means I can prevent 90% of kidney failure around the world.

I'm sorry to say that the news has been, in effect, suppressed. The media wouldn't publish anything unless another nephrologist endorsed the paper. No nephrologist has endorsed the paper because it means the end of a $40 billion a year industry. Details are at http://tinyurl.com/healthcrime.

I'm now putting together a class-action lawsuit. Anybody who went on dialysis after 2006, I could have prevented, had the appropriate medical authorities simply done their job and informed the public about my 2002 paper. So I'm looking for dialysis patients who went on after 2006. Please contact me.

Best regards,
Dave Moskowitz MD
CEO, GenoMed, Inc. (www.genomed.com)

References
1:  Moskowitz DW. Is angiotensin I-converting enzyme a "master" disease gene? Diabetes Technol Ther. 2002;4(5):683-711. PMID: 12458570 (http://www.genomed.com/pdf/is.angiotensin.pdf)
2:  Moskowitz DW. From pharmacogenomics to improved patient outcomes: angiotensin I-converting enzyme as an example. Diabetes Technol Ther. 2002;4(4):519-32. PMID: 12396747. (http://www.genomed.com/pdf/diabetes.technology.therapeutics.pdf).

[cariad]

Hello and 

I have to admit that statements like this bring out the sceptic in me:
 

Anybody who went on dialysis after 2006, I could have prevented, had the appropriate medical authorities simply done their job and informed the public about my 2002 paper.

From the small bit of Internet research that I just did on this, it says that you showed that you can slow kidney decline in diabetics. I was on lisinopril for a number of years, and my nephrologist told me that it does preserve kidney function but will raise my creat. Sure enough, that is exactly what it did. It eventually brought my blood pressure dangerously low, and I had to stop taking it. I did not think it was a big secret that ACE inhibitors can slow kidney decline. Are you saying that it should have been able to stop my decline completely?

I was on dialysis after 2006 (but I have no interest in joining a class action, and I am not diabetic). My interest in what you are claiming is purely intellectual curiosity.

[DianaJean6]

I agree its no big secret that ACE inhibitors slow the progression of kidney disease in diabetics.  I was given Lisinopril pre-menopausal but my blood pressure drop dangerously low.  Post menopausal, I got the famous Lisinopril cough (sounds like whooping cough).  The idea that you could make the world dialysis free is a sweet dream.

[RichardMEL]

I am not diabetic.

I am also convinced that going on an ACE inhibitor in 1993 when I was diagnosed gave me many extra years of kidney function and slowed down the damage FSGS was doing to my kidneys. I was on the lowst dose of Coversyl (2mg at the time) and my BP was very well controlled.

[Zach]

Still don't see your point here.

 

[Rerun]

I say go for it.  Just like big oil put a stop to a distributor that would go 100 miles per gallon I truly believe that if someone had the cure for kidney disease they would be dissappeared!  Too much money for them to cure it. 

I've been on for way too long, but good luck.  Glad you found us.

Rerun, Moderator        

[Bajanne]

Welcome to our community!  I must say it sounds interesting - but that is all I can say!  I started dialysis in 2005 so I am out of the loop.  Good luck with your research.







Bajanne, Moderator

[fc2821]

   Daid, best of luck and hopefully your discovery will help many!    I can't join your suit.  Your process would not have helped keep me from dialysis, I dloosid notloose my kidenys due to disease, butsevere injury.
   Welcome to the group   

[DrMoskowitz]

Lisinopril, which has captured the generic market, probably because it was the cheapest ACE inhibitor 10 yrs ago and managed care plans adopted it en masse, does NOT prevent kidney failure. I don't even think it slows it down. In my experience, only a few ACE inhibitors can actually REVERSE early-stage kidney failure. Lisinopril can't do it. Plus, the dose is absolutely critical. Low dose lisinopril doesn't do a thing.

It's quite possible that FSGS behaves like NIDDM and hypertension, i.e. that renal failure can be reversed with the right dose of the right ACE inhibitor. I haven't had any FSGS patients to try it in. No FSGS patients have ever heard about me, nor have any other kidney failure patients, for that matter.

IF it suddenly became known that I had been able to prevent 90% of kidney failure among my 1350 patients over the past 15 yrs, then I think my goal of making the world dialysis-free in 5 yrs would be realizable.

At least this is the only website where people make no bones about their dislike for dialysis. Every other kidney organization is funded by DaVita, Amgen, and Fresenius, and promotes the wonders of dialysis.

[Romona]

 

[noahvale]

***

[mogee]

If you aren't a patient or caring for one in your family you have no business on this site.  Besides, moron, ACE inhibitors have been well known to retard primary kidney disease for more than a decade.  It is not appropriate to fish this site for your own professional advancement.

[RichardMEL]

I'm interested to hear exactly what ACE inhibitors and at what dose you think are good for "reversing" or at least slowing/halting the progression of FSGS? I was on Coversyl 2mg, then 4mg then eventually 2.5mg for 14 years from when I was diagnosed with FSGS in 1993 till I started D in 2006. I am convinced after some investigations that that was a prime factor in keeping my chronic FSGS at bay for so long and giving me more years of a more normal lifestyle. I am obviously thus interested in your thoughts on this since should I get a transplant the reoccurance of FSGS is thus a concern, so anything that could potentially again keep that at bay would be of personal interest to me.

[okarol]

Dr.Moskowitz;
This is the intro section so please take any further discussion to a new thread.

If you aren't a patient or caring for one in your family you have no business on this site.  Besides, moron, ACE inhibitors have been well known to retard primary kidney disease for more than a decade.  It is not appropriate to fish this site for your own professional advancement.

mogee,
This site is for everyone related to CKD, personally or professionally. The admin team monitors the discussions and if a member crosses the line we will address it. Thanks.

okarol/admin