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Author Topic: Immunosuppressants and skin cancer  (Read 2513 times)
okarol
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Photo is Jenna - after Disneyland - 1988

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« on: May 17, 2008, 11:36:08 AM »

Immunosuppressants and skin cancer

Squamous cell carcinoma is the second most common type of skin cancer.  It appears as pink-to-red scaly growths usually on sun-exposed surfaces such as the scalp, face, ears, hands, and arms.

It is estimated that one in five Americans will develop skin cancer during their lifetime.  Approximately one million new skin cancers are diagnosed each year in the United States. Eighty percent are basal cell carcinoma, 16% are squamous cell carcinoma and 4% are melanoma.  (Statistics provided by the American Academy of Dermatology.)

Risk factors for squamous cell carcinoma include fair skin, freckles, blue eyes and blonde hair. Environmental factors such as excessive ultraviolet light exposure from the sun or tanning booths also present a high risk.

People on immunosuppressant medications such as organ transplant patients are particularly susceptible.  Other important factors increasing susceptibility to squamous cell include occupational x-ray exposure, environmental exposure to coal or chemicals such as arsenic and scarring from trauma, diseases or burns.  Finally, family history plays an important role as some individuals are more susceptible to skin cancer.

The cure rate for squamous cell carcinoma is approximately 95% when treated properly.  The tumor should be treated by a dermatologist or plastic surgeon.  The extent and type of treatment depends on the characteristics, size and location of the tumor.

Sun avoidance, protection and sunscreen are the basics of good skin care.

During the summer, limiting the length of time spent outdoors between 11am and 4pm, wearing wide-brimmed hats and clothing to shade the skin and applying an SPF 15 or higher,  broad-spectrum sunscreen will go a long way in helping to prevent skin cancer.

Here are some protective clothing resources:
http://www.spfstore.com/
http://www.shadyladyproducts.com/
http://www.sunprotection.com/
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Admin for IHateDialysis 2008 - 2014, retired.
Jenna is our daughter, bad bladder damaged her kidneys.
Was on in-center hemodialysis 2003-2007.
7 yr transplant lost due to rejection.
She did PD Sept. 2013 - July 2017
Found a swap living donor using social media, friends, family.
New kidney in a paired donation swap July 26, 2017.
Her story ---> https://www.facebook.com/WantedKidneyDonor
Please watch her video: http://youtu.be/D9ZuVJ_s80Y
Living Donors Rock! http://www.livingdonorsonline.org -
News video: http://www.youtube.com/watch?v=J-7KvgQDWpU
monrein
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« Reply #1 on: May 17, 2008, 12:32:54 PM »

This is really important information and is something that my neph has always warned me about since I am very fair, blue-eyed (we looked almost albino as kids) and since my Mum died young of melanoma.  I always wear a hat for gardening and when I used to do wilderness canoeing I'd always wear long sleeves and even paddling gloves as well for protection.  Heavy duty sunscreen every day even in winter and finally, I see a dermatologist usually every one to two years and she burns suspicious things off me.  Just had three spots done and a bunch of warts on my feet at the same time.  Yep, body maintenance has become a full and part time job for this body.
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Pyelonephritis (began at 8 mos old)
Home haemo 1980-1985 (self-cannulated with 15 gauge sharps)
Cadaveric transplant 1985
New upper-arm fistula April 2008
Uldall-Cook catheter inserted May 2008
Haemo-dialysis, self care unit June 2008
(2 1/2 hours X 5 weekly)
Self-cannulated, 15 gauge blunts, buttonholes.
Living donor transplant (sister-in law Kathy) Feb. 2009
First failed kidney transplant removed Apr.  2009
Second trx doing great so far...all lab values in normal ranges
okarol
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Photo is Jenna - after Disneyland - 1988

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« Reply #2 on: May 17, 2008, 01:58:37 PM »


Jenna is required to have annual skin cancer checks by a dermatologist as part of her transplant program. She is also blonde, blue-eyed and very fair. They said the part in a person's hair is very vulnerable as it's exposed all the time.
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Admin for IHateDialysis 2008 - 2014, retired.
Jenna is our daughter, bad bladder damaged her kidneys.
Was on in-center hemodialysis 2003-2007.
7 yr transplant lost due to rejection.
She did PD Sept. 2013 - July 2017
Found a swap living donor using social media, friends, family.
New kidney in a paired donation swap July 26, 2017.
Her story ---> https://www.facebook.com/WantedKidneyDonor
Please watch her video: http://youtu.be/D9ZuVJ_s80Y
Living Donors Rock! http://www.livingdonorsonline.org -
News video: http://www.youtube.com/watch?v=J-7KvgQDWpU
monrein
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« Reply #3 on: May 17, 2008, 02:21:13 PM »

Good point about the scalp Karol.  I go regularly to have my hair done and my stylist checks my scalp carefully as she does my highlights.  When I was first transplanted I saw the dermatologist annually but as time went on I went every couple of years or more often if I found something suspicious.
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Pyelonephritis (began at 8 mos old)
Home haemo 1980-1985 (self-cannulated with 15 gauge sharps)
Cadaveric transplant 1985
New upper-arm fistula April 2008
Uldall-Cook catheter inserted May 2008
Haemo-dialysis, self care unit June 2008
(2 1/2 hours X 5 weekly)
Self-cannulated, 15 gauge blunts, buttonholes.
Living donor transplant (sister-in law Kathy) Feb. 2009
First failed kidney transplant removed Apr.  2009
Second trx doing great so far...all lab values in normal ranges
Chris
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« Reply #4 on: May 18, 2008, 03:23:42 PM »

My transplant center started having me see a dermatologist who specializes in seeing transplant patients after 5 years post transplant. The doctor prescribes Tretinoin Cream, USP 0.05% to help prevent skin cancer that is applied everyday at night. But it smells bad to me.
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Diabetes -  age 7

Neuropathy in legs age 10

Eye impairments and blindness in one eye began in 95, major one during visit to the Indy 500 race of that year
   -glaucoma and surgery for that
     -cataract surgery twice on same eye (2000 - 2002). another one growing in good eye
     - vitrectomy in good eye post tx November 2003, totally blind for 4 months due to complications with meds and infection

Diagnosed with ESRD June 29, 1999
1st Dialysis - July 4, 1999
Last Dialysis - December 2, 2000

Kidney and Pancreas Transplant - December 3, 2000

Cataract Surgery on good eye - June 24, 2009
Knee Surgery 2010
2011/2012 in process of getting a guide dog
Guide Dog Training begins July 2, 2012 in NY
Guide Dog by end of July 2012
Next eye surgery late 2012 or 2013 if I feel like it
Home with Guide dog - July 27, 2012
Knee Surgery #2 - Oct 15, 2012
Eye Surgery - Nov 2012
Lifes Adventures -  Priceless

No two day's are the same, are they?
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