When I'm done my manual drain I just rest the bag on the vanity and let it drain into the toilet. When it's done I hold it up a second to drain the last few drops out and then roll the bag up, continuing with the hose around the rolled up bag and toss it in the trash. I haven't had a leak in the house yet and when rolling up the bags I can fit a lot more in the trash then I could when I just tossed the empty's in the can.The only spill I had was while taking them to the clinic for my second test. I placed the box on the passanger seat of my car and I guess a clamp came off. It took about 2 month's and several interior hose downs to get rid of that smell as it was still the end of the summer so it kind of got cooked. I have since learned to just take my truck and throw the box in the back whenever I have to take a sample in. I also make sure to pinch the hose in the corner of the box flaps for added security.