Hello UKrainian Tracksuit,
This is a difficult question to answer, especially since we don't really know what "seeps" through the skin into our system!
Perhaps it would not be such a good idea to use grapefruit on the skin since it is a no-no to eat grapefruit with transplant medication and because of that I personally would not entertain the idea to use it on my skin either.
For many years I have used once every week a "Manuka Honey Peel-Off Mask" to clean my skin thoroughly and it has worked well so far, especially since my dialysis-unit is air-conditioned and my skin does not like air-conditioning, but with my weekly "Manuka Honey Peel-Off Mask" my skin is able to tolerate the air-conditioning a little better.
Good luck wishes from Kristina.