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Author Topic: Thank you NxStage  (Read 16405 times)
obsidianom
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« Reply #50 on: April 26, 2014, 08:05:54 AM »

Another advantage to near daily dialysis such as Nxstage is removal of uremic toxins that are protein boundand and hard to remove.

"Removal of indoxyl sulphate and p-cresyl sulphate(p-cresol) can be improved to some extent by increasing the diffusion of the free forms with super-flux membrane HD, increasing the dialyzer transfer area coefficient and dialysate flow, haemodiafiltration,daily HD,------"

Notice that last 2 words, daily HD.  These toxins are very hard to remove with standard 3 day dialysis unless there is more time .


On the other hand note this :

"p-Cresol is a major component in pig odor.[2]
 
p-Cresol is a component in human sweat. It is a component of human odor attractive to female mosquitoes.[3]
 
Temporal glands secretion examination showed the presence of phenol and p-cresol during musth in male elephants.[4][5]"

So guys and gals, we are full of p-cresol that is hard to dialyze out and its in pig sweat, human odor that attracts FEMALE mosquitoes, and male elaphants in musth. There are a WHOLE lot of wise ass remarks I can make about this. Especially to guys and pigsweat and attraction to females----oops , mosquitoes. and like elephant musths.
So the moral of the story, DAILY DIALYSIS TO REDUCE PROTEIN BOUND P-CRESOL or you smell like pig sweat and attract female mosquitoes while in musth.
« Last Edit: April 26, 2014, 08:22:00 AM by obsidianom » Logged

My wife is the most important person in my life. Dialysis is an honor to do for her.
NxStage since June 2012 .
When not doing dialysis I am a physician ,for over 25 years now(not a nephrologist)

Any posting here should be used for informational purposes only . Talk to your own doctor about treatment decisions.
Speedy1wrc
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« Reply #51 on: April 26, 2014, 03:57:18 PM »

All smart remarks aside, I think the biggest keys are as we all know time and dialysate flow. If you do in center for three hours or at home for three hours I don't know if there would be a statistical difference. I do think frequency obviously matters as you aren't so far behind the with ball each treatment. I can see it inasmuch as I have greatly reduced my blood pressure medicine since being on home hemo. In center my dosages were increasing after a year, and now at home after a year, I am almost completely off any blood pressure medicine.
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amanda100wilson
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« Reply #52 on: April 26, 2014, 06:00:06 PM »

Just Before my diagnosis of CKD was made, many 'eons' ago when We were living in Hong Kong, I used to get bitten very badly by mosquitoes, much more so than my husband.  After that we moved to Cyprus, and when I went outside, I used to have a swarm of flies around my head, like PigPen out of the Peanuts stories.  I always attributed it yo abnormal blood chemistry.

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ESRD 22 years
  -PD for 18 months
  -Transplant 10 years
  -PD for 8 years
  -NxStage since October 2011
Healthy people may look upon me as weak because of my illness, but my illness has given me strength that they can't begin to imagine.

Always look on the bright side of life...
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