Hi Haz! I have PKD too and am scheduled to have a bi-later nephrectomy (removal of both kidneys) on Oct. 1st. Like you, I have the back pain, trouble breathing at times, and just have that uncomfortable feeling all the time. I am currently doing NxStage home hemo 5 days a week, avg. 2.5 - 3 hrs each.I have been told that the PKD would still be there after the surgery but it doesn't affect the other organs like it does the kidneys and it also won't hurt anew transplanted kidney. I'm told the surgery will be about 6 hrs and I'll be in the hospital 4-7 days. I understand there will be a significant incision that takes some time to fully heal but, I figure it will be worth it just to loose all pain & discomfort from the kidneys themselves. I plan on having my laptop at the hospital and will try to update my progress as I'm able.How long have you known you have PKD & how long have you been on D? Do you know how big you kidneys are? I'm told mine are 40 pounds each.Very hard for me to believe. I've asked for pictures of them and have been assured I will get them. Feel free to ask any questions you have. I'll answer all that I can.Wishing you well,Lorie