hyponatremia

[shivashankerprasad]

 I am a CAPD dialysis patient and i want to know whether use of diuretics {Frusemide}  promotes hyponatremia{low sodium level}.
My serum sodium level is 128 mmol/L resulting in too low blood pressure and convulsions{body shaking}
my salt intake is 4gm per day plus indirect intake.
night dwell promotes sodium loss?

[angieskidney]

I am a CAPD dialysis patient and i want to know whether use of diuretics {Frusemide}  promotes hyponatremia{low sodium level}.
My serum sodium level is 128 mmol/L resulting in too low blood pressure and convulsions{body shaking}
my salt intake is 4gm per day plus indirect intake.
night dwell promotes sodium loss?

That is an interesting question. Mind if I post that on a medical site I moderate which is run by a dialysis nurse in Ohio? I figure he might know.

I don't know the answer myself but I don't think night dwells are a problem (unless your magnesium levels are not right). But I can't rule out that furosemide wouldn't cause low sodium levels in some people so you might want to check out this site (I had been on it before as well. Click the name to look up the drug precautions. Also referred to as Lasix®).

http://www.medicinenet.com/furosemide/article.htm

Furosemide can cause lowering of blood potassium, sodium, and magnesium levels.

It sounds as if you really should stop that drug or perhaps lower the dose. You should never take it once your urine output has stopped but it does help to keep taking it before urine output completely stops.

You might also want to check out this site as well:

• http://telinco.net/lifestyle/healthfitness/health_advice/netdoctor/archive/100003257.html
• http://telinco.net/lifestyle/healthfitness/health_advice/netdoctor/archive/100001106.html

How does it work?

This medicine contains the active ingredient frusemide (also known as furosemide), which is a type of medicine called a loop diuretic. Loop diuretics act in the kidney to remove excess water from the blood, by causing an increase in the removal of salts such as potassium and sodium. This removal of salts causes water to be drawn out of the blood and into the kidneys, where it is then excreted in the urine. Removing water from the blood causes a decrease in the volume of fluid circulating through the blood vessels. This drop in fluid volume decreases the effort required by the heart to pump blood around the body. There are many conditions which may lead to an accumulation of fluid in the body (oedema).

Warning!

• It is recommended that individuals taking this medicine have their fluid and salt (electrolyte) balance monitored regularly
• If you experience any of the following symptoms while taking this medicine you should inform your doctor promptly, so that the amount of fluids and salts in your body can be checked: thirst, lethargy, confusion, weakness, drowsiness, muscle cramps, scanty production of urine, abnormal heart rhythm, seizures, nausea and vomiting.
• As diuretics cause your kidneys to produce more urine, you may prefer to take this medicine in the morning rather than before going to bed, as this will reduce the likelihood of you needing to get up in the night to visit the toilet. Seek further advice from your doctor or pharmacist.

.

I would think that low blood pressure and convulsions would be included as it sounds like dehydration.

Use with caution in:
[LI]Breastfeeding [/li]
[LI]Diabetes[/li]
[LI]Difficulty in passing urine (urinary retention) [/li]
[LI]Enlarged prostate gland[/li]
[LI]Low blood potassium levels (hypokalaemia) [/LI]
[LI]Low blood pressure (hypotension) [/LI]
[LI]Low blood sodium levels (hyponatraemia) [/LI]
[LI]Low volume of circulating blood (hypovolaemia) [/LI]
[LI]Pregnancy[/LI] [/list]

** As with any advice online, always talk to your doctor.

[BigSky]

I am a CAPD dialysis patient and i want to know whether use of diuretics {Frusemide}  promotes hyponatremia{low sodium level}.
My serum sodium level is 128 mmol/L resulting in too low blood pressure and convulsions{body shaking}
my salt intake is 4gm per day plus indirect intake.
night dwell promotes sodium loss?

My understanding of furosemide works by forcing the kidneys to produce more urine.  If you kidneys no longer work I am not sure it would be having any effect.

[shivashankerprasad]

i still have some reidual renal function {about 10%} so i do produce substantial quantity of urine.
i think aggresive use  of frusemide made me lose more sodium resulting in hyponatremia.
My neph told me that hyponatremia is a serious disorder if sr sodium level becomes less then 125mmol/L.
u can have mental disorientation,body seizures{just like epilepsy} even coma and death.
so i have stopped loop diuretics and my hypertensive medication dose is also readjusted.
now i m feeling fine

[angieskidney]

i still have some reidual renal function {about 10%} so i do produce substantial quantity of urine.
i think aggresive use  of frusemide made me lose more sodium resulting in hyponatremia.
My neph told me that hyponatremia is a serious disorder if sr sodium level becomes less then 125mmol/L.
u can have mental disorientation,body seizures{just like epilepsy} even coma and death.
so i have stopped loop diuretics and my hypertensive medication dose is also readjusted.
now i m feeling fine

Oh I am soooo glad! I was worried about you! I am glad you got it looked into right away!