Meat Additives Could Harm Kidney Patients By Kristina Fiore, Staff Writer, MedPage Today
Published: July 24, 2009
Reviewed by Zalman S. Agus, MD; Emeritus Professor
University of Pennsylvania School of Medicine. Earn CME/CE credit
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LITTLE FALLS, N.J., July 24 -- Uncooked meat and poultry products enhanced with phosphate salts may contain excessive amounts of phosphorus and potassium that could affect patients with kidney disease, researchers say.
Action Points
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■Explain that meat and poultry products with added phosphate salts had a phosphate-to-protein ratio that was 28% higher than products with no additives.
■Note that the additives could make it hard for patients with kidney disease to limit their daily phosphorus and potassium intake.
Meats with additives had an average phosphate-to-protein ratio 28% higher than products with no additives, Richard A. Sherman, MD, and Ojas Mehta, MD, of the University of Medicine and Dentistry of New Jersey, reported online in the Clinical Journal of the American Society of Nephrology.
The additives could make it difficult for patients with kidney disease to limit dietary phosphorus and potassium intake, the researchers said.
"The burden imposed on those who seek to limit dietary phosphorus and potassium could be ameliorated by more complete food labeling by manufacturers," they said.
Controlling dietary phosphorus intake is a challenge for dialysis patients who have to be wary of hyperphosphatemia because meat and poultry enhanced with phosphate salts are not always labeled as such.
While 11 different phosphate salts are currently approved for use in meat and poultry (six are sodium salts and five are potassium salts), there's no requirement that this information be displayed on nutrition labels.
So the researchers measured the phosphorus, potassium, and protein content of 36 uncooked meat and poultry products purchased at supermarkets.
They found that products that reported using additives had an average phosphate-to-protein ratio that was 28.4% higher than additive-free products. In fact, the content ranged up to almost 100% higher.
Potassium content ranged widely, but averaged 8.7% higher than regular products. And while additive-free products contained fewer than 387 mg per 100 g of protein, five of the 25 products with additives contained at least 692 mg/100g.
The researchers say the findings draw attention to potassium additives, which have not received as much attention as added sodium and phosphorus in processed foods.
In some cases, the added amount of potassium is "striking," the researchers said.
One sample had 930 mg per 100 g of protein, a level "three-fold higher than a similar product," they said.
"Thus, a 200-g portion would contain almost 2 g of potassium, most of a dialysis patient's daily restricted intake."
That could put dialysis patients at increased risk of for developing hyperkalemia, and its origin "would very likely be unrecognized," the researchers said. "More attention to [added] potassium is warranted."
Most, but not all foods with phosphate and potassium additives reported their content on product labeling, with 16 of 25 listing the specific additives.
The impact of enhancing meat and poultry products with phosphate salts is likely to be clinically significant, the researchers said, as it may affect phosphate-binding requirements.
Phosphates not removed by dialysis must be removed by binders, thus increasing binder requirements, they said.
They concluded that food-processing companies need to disclose the type and amount of additives in meat and poultry products.
The researchers reported no conflicts of interest.
Primary source: Clinical Journal of the American Society of Nephrology
Source reference:
Sherman RA, Mehta O "Phosphorus and potassium content of enhanced met and poultry products: Implications for patients who receive dialysis" Clin J Am Soc Nephrol 2009; DOI: 10.2215/CJN.02830409.
http://www.medpagetoday.com/PrimaryCare/DietNutrition/15238