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Author Topic: Post Transplant Elevated Liver  (Read 4719 times)
rookiegirl
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« on: June 04, 2009, 06:41:37 AM »
Since I had my transplant in March 2009, my clinic have been monitoring my Liver function.  On my 2nd clinic visit, they mentioned about my liver enzyme and wanted to do an ultrasound of my liver and gall bladder.  After the ultrasound, they didn't find anything out of the ordinary.  My Liver is elevated due to the medications I'm taking so they will monitor.

I received my lab results yesterday:  Creatinine 1.4, Hemoglobin 12.7, Prograf level 7.8, Liver test elevated.

My question to those that received transplant, did you ever had the same problem with your liver as me?  Prior to my transplant, I never had any issue with my liver or any other parts of my body except my kidneys.  I'm scared if they can't control my liver that I have another issue at hand.
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2000-Diagnosed IGA Nephropathy
2002-1st biopsy (complications)
2004-2nd biopsy
10/03/07-Tenckhoff Catheter Placement
10/22/07-Started Peritoneal Dialysis
03/2008-Transplant team meeting
04/2008-Transplant workup
05/2008-Active Transplant list
3/20/09-Cadaver Kidney Transplant
4/07/09-Tenckhoff Catheter removed
4/20/09-New kidney biopsy
monrein
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« Reply #1 on: June 04, 2009, 08:45:35 AM »
Many of my liver enzymes are somewhat elevated too RG but they're not too concerned so far.  My liver is a bit wonky, the right lobe has some damage from a virus that I never even knew about many years ago.  Obviously the levels must be monitored but don't worry too much about this since that won't help the liver enzyme tests any.  I do think it's the drugs we take especially since generally they try to avoid drugs that are metabolized through the kidney in favour of ones that are handled by the liver.   Welcome to the transplant tightrope.  It beats the dialysis roller coaster.
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Pyelonephritis (began at 8 mos old)
Home haemo 1980-1985 (self-cannulated with 15 gauge sharps)
Cadaveric transplant 1985
New upper-arm fistula April 2008
Uldall-Cook catheter inserted May 2008
Haemo-dialysis, self care unit June 2008
(2 1/2 hours X 5 weekly)
Self-cannulated, 15 gauge blunts, buttonholes.
Living donor transplant (sister-in law Kathy) Feb. 2009
First failed kidney transplant removed Apr.  2009
Second trx doing great so far...all lab values in normal ranges
rookiegirl
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« Reply #2 on: June 04, 2009, 10:14:45 AM »
Thanks for the information.  Good to know that I'm not alone concerning my liver issue.  I pray it doesn't get worst.

I wonder if there is anything I can do for myself to help my liver (special diet, exercise, etc...).
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2000-Diagnosed IGA Nephropathy
2002-1st biopsy (complications)
2004-2nd biopsy
10/03/07-Tenckhoff Catheter Placement
10/22/07-Started Peritoneal Dialysis
03/2008-Transplant team meeting
04/2008-Transplant workup
05/2008-Active Transplant list
3/20/09-Cadaver Kidney Transplant
4/07/09-Tenckhoff Catheter removed
4/20/09-New kidney biopsy
donnia
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« Reply #3 on: June 04, 2009, 07:06:38 PM »
That happened to me as well.  Are you taking anything for Cholesterol???  I was taking Lipitor and it was the culprit. 

Good Luck!!!! :flower;
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Born with one kidney 1972
Ureter re-constructured 1975 (reflux had already damaged the kidney)
Diagnosed and treated for high blood pressure 2000
Diagnosed ESRF October 2006
Started dialysis September 2007
Last dialysis June 4, 2008
Transplant from my hero, Joyce, June 5, 2008
Chris
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« Reply #4 on: June 04, 2009, 11:56:53 PM »
Have they tested for CMV?
When my liver level went up, they did the same old monthly test and just monitored it. Then it rose more and more and my liver became painful. Shortend of the story my transplant center finally did a liver biopsy and CMV blood test.

I was on Gancyclovir/Cytovene post tx for 3 months then stopped and shortly after that I began th rollercoaster. So keep any eye on your labs, note any changes the way your body feels and tell your doctor or transplant team.

Good Luck
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Diabetes -  age 7

Neuropathy in legs age 10

Eye impairments and blindness in one eye began in 95, major one during visit to the Indy 500 race of that year
   -glaucoma and surgery for that
     -cataract surgery twice on same eye (2000 - 2002). another one growing in good eye
     - vitrectomy in good eye post tx November 2003, totally blind for 4 months due to complications with meds and infection

Diagnosed with ESRD June 29, 1999
1st Dialysis - July 4, 1999
Last Dialysis - December 2, 2000

Kidney and Pancreas Transplant - December 3, 2000

Cataract Surgery on good eye - June 24, 2009
Knee Surgery 2010
2011/2012 in process of getting a guide dog
Guide Dog Training begins July 2, 2012 in NY
Guide Dog by end of July 2012
Next eye surgery late 2012 or 2013 if I feel like it
Home with Guide dog - July 27, 2012
Knee Surgery #2 - Oct 15, 2012
Eye Surgery - Nov 2012
Lifes Adventures -  Priceless

No two day's are the same, are they?
rookiegirl
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« Reply #5 on: June 05, 2009, 05:39:29 AM »
I've never been on Cholesterol meds.  I will definitely mention to my clinic about testing for CMV.  I really hope they don't have to do a biopsy of my liver.  I just hate biopsy of anything.
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2000-Diagnosed IGA Nephropathy
2002-1st biopsy (complications)
2004-2nd biopsy
10/03/07-Tenckhoff Catheter Placement
10/22/07-Started Peritoneal Dialysis
03/2008-Transplant team meeting
04/2008-Transplant workup
05/2008-Active Transplant list
3/20/09-Cadaver Kidney Transplant
4/07/09-Tenckhoff Catheter removed
4/20/09-New kidney biopsy
paris
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« Reply #6 on: June 05, 2009, 10:54:06 AM »
AlohaBeth had elevated liver levels.  After many blood tests, they linked it to the tylenol, etc she was taking for herniated discs.   Could it be becasue of any meds you are on right now?  Hope they finda an answer quick (without a biopsy!!)
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rookiegirl
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« Reply #7 on: June 05, 2009, 11:14:50 AM »
Quote from: paris on June 05, 2009, 10:54:06 AM
AlohaBeth had elevated liver levels.  After many blood tests, they linked it to the tylenol, etc she was taking for herniated discs.   Could it be becasue of any meds you are on right now?  Hope they finda an answer quick (without a biopsy!!)

They did mention it's most likely the meds I'm taking post transplant until I they reduce it down.  They will continue to monitor.  I guess monitoring means it's not alarming yet and no need to PANIC.
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2000-Diagnosed IGA Nephropathy
2002-1st biopsy (complications)
2004-2nd biopsy
10/03/07-Tenckhoff Catheter Placement
10/22/07-Started Peritoneal Dialysis
03/2008-Transplant team meeting
04/2008-Transplant workup
05/2008-Active Transplant list
3/20/09-Cadaver Kidney Transplant
4/07/09-Tenckhoff Catheter removed
4/20/09-New kidney biopsy
rookiegirl
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« Reply #8 on: June 16, 2009, 07:45:21 AM »
Quote from: Chris on June 04, 2009, 11:56:53 PM
Have they tested for CMV?
When my liver level went up, they did the same old monthly test and just monitored it. Then it rose more and more and my liver became painful. Shortend of the story my transplant center finally did a liver biopsy and CMV blood test.

I was on Gancyclovir/Cytovene post tx for 3 months then stopped and shortly after that I began th rollercoaster. So keep any eye on your labs, note any changes the way your body feels and tell your doctor or transplant team.

Good Luck

Chris - you mentioned "liver became painful", how painful and where exactly did you feel the pain?  In the last 2-3 day, I've been feeling soreness on my upper right side near the rib area.  I thought maybe I slept wrong since I'm a side sleeper.  Then I thought maybe it's my liver?  I'm not exactly sure the location of the liver.  Stupid I know.
Logged
2000-Diagnosed IGA Nephropathy
2002-1st biopsy (complications)
2004-2nd biopsy
10/03/07-Tenckhoff Catheter Placement
10/22/07-Started Peritoneal Dialysis
03/2008-Transplant team meeting
04/2008-Transplant workup
05/2008-Active Transplant list
3/20/09-Cadaver Kidney Transplant
4/07/09-Tenckhoff Catheter removed
4/20/09-New kidney biopsy
Chris
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« Reply #9 on: June 16, 2009, 05:38:19 PM »
That is about the area I was feeling pain, at the lower rib cage and just below it. It was very sensitive to touch, more than normal for me that is. The pain did nt go away until treatment was given after a few weeks.
Bring it up with your doctor if it doesn't go away and ask what they have tested for so far.
Logged
Diabetes -  age 7

Neuropathy in legs age 10

Eye impairments and blindness in one eye began in 95, major one during visit to the Indy 500 race of that year
   -glaucoma and surgery for that
     -cataract surgery twice on same eye (2000 - 2002). another one growing in good eye
     - vitrectomy in good eye post tx November 2003, totally blind for 4 months due to complications with meds and infection

Diagnosed with ESRD June 29, 1999
1st Dialysis - July 4, 1999
Last Dialysis - December 2, 2000

Kidney and Pancreas Transplant - December 3, 2000

Cataract Surgery on good eye - June 24, 2009
Knee Surgery 2010
2011/2012 in process of getting a guide dog
Guide Dog Training begins July 2, 2012 in NY
Guide Dog by end of July 2012
Next eye surgery late 2012 or 2013 if I feel like it
Home with Guide dog - July 27, 2012
Knee Surgery #2 - Oct 15, 2012
Eye Surgery - Nov 2012
Lifes Adventures -  Priceless

No two day's are the same, are they?
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