I Hate Dialysis Message Board
Dialysis Discussion => Dialysis: Transplant Discussion => Topic started by: robertscz on October 24, 2017, 09:06:32 AM
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was reading today and found this article from new england journal of medicine. they took all 90k + transplant recipients and did a study between 1988 and 1996. they found the projected half life of living donors rose from 12.7 in 1988 to 21.6 in 1996 and deceased donors rose from 7.9 in 1988 to 13.8 in 1996.
now here is the most important part!!
they then filtered out the patients who had died WITH A FUNCTIONING GRAFT!!!! these results are staggaring:
the half life went from 16.9 years in 1988 to 35.9 years in 1996 from living donors
half life of 11 years in 1988 to 19.5 years in 1996 from deceased donors
i find this very interesting because most times the statistics dont filter out those that passed away from a cause with a functioning transplanted kidney, this one did. and this study was done in 1996, so 20 years later, these numbers are probably even higher. great article and easy to understand for those that are interested in reading it in its entirety!!
http://www.nejm.org/doi/pdf/10.1056/NEJM200003023420901
here is the "results" section copied and pasted:
Table 2 shows the projected half-life of all transplants,
with and without the censoring of data for
patients who died with functioning grafts, from 1988
to 1995. The projected half-life for transplants from
living donors was 12.7 years in 1988 and 21.6 years
in 1995, representing an increase of 70 percent in
1995. After the censoring of data for patients who
died with functioning grafts, the respective values were
16.9 years in 1988 and 35.9 years in 1995, representing
an increase of 112 percent. The projected halflife
for transplants from cadaveric donors was 7.9 years
in 1988 and 13.8 years in 1995, representing an increase
of 75 percent in 1995. After the censoring of
data for patients who died with functioning grafts,
the respective half-lives were 11.0 years and 19.5 years,
representing an increase of 77 percent
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Good information, and even better that is from 17 years ago! So our odds should be even better (assuming new technologies and transplant processes are better).
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am i the only one that finds this very encouraging? or am i missing something to where this is incorrect information?
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One thing that is interesting is that they give two half lives - one excluding non-renal deaths and one that includes all deaths. When you exclude non-renal deaths of a xplant recipient, the numbers look a bit better.
Overall, a very encouraging article.