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Dialysis Discussion => Dialysis: News Articles => Topic started by: okarol on January 29, 2011, 11:50:10 PM
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Vascular access for hemodialysis in the elderly
Nicola Swindlehurst, MBBS, Andrew Swindlehurst, MBBS, Heather Lumgair, MBBS, Irene Rebollo Mesa, PhD, Nizam Mamode, MB FRCS, Roberto Cacciola, MBBS, MD, FRCS, Iain Macdougall, MBChB MD FRCP
Received 26 January 2010; accepted 28 September 2010. published online 10 January 2011.
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Abstract Full Text PDF Images References
Objective:
The number of elderly patients needing hemodialysis is constantly increasing year by year. Elderly patients with end-stage renal failure represent a challenge for the surgeons who create vascular accesses. The aim of this study was to analyze the outcome of conduit creation in the elderly in our institution and to compare it with the outcome of a cohort of patients aged <65 years.
Methods:
The study was performed retrospectively on prospectively collected data. The study period was between January 1, 2000, and December 31, 2006. We identified first attempts at conduit creations, including arteriovenous fistulas (AVFs) and grafts, in elderly patients (aged ≥65 years) who were allocated to group A, and in nonelderly patients (<65 years) who were allocated to group B. Subsequent attempts at conduit creations in the same patient were omitted from the data set.
Results:
There were 246 first AVFs in group A and 89 in group B. At a mean follow-up of 25.46 months (SD, 18.93 months), the primary patency (PP) rate of all AVFs was 70% in group A and 68% in group B (P = .75). The assisted PP rate was 73% in group A and 77% in group B (P = .4). The secondary patency (SP) rate was 73% in group A and 79% in group B (P = .9). Also, the differences in the 12-month cumulative patency rates (including PP, assisted PP, and SP) in the two groups (65% vs 60%) were not significant. At a mean follow-up of 25 months, death with a functioning conduit occurred at the same rate in both groups (56% and 54%), and mean conduit survival did not differ according to age (516 and 511 days). The incidence of failure to mature was higher in group A (6.1% vs 1.1%, P = .03). Patency rates for different types of conduits were similar between the two groups, although polytetrafluoroethylene grafts had a higher cumulative patency in group A (94% vs 69%; P = .05). The rate of procedures to salvage conduits was 2.5% in group A vs 10.1% in group B. Mean hospital stay for group A and group B was 3.2 days.
Conclusions:
In our experience, the creation of permanent hemodialysis access in the elderly with AVF is not only possible but also proved to have a short hospital stay, high patency rates, and an acceptable rate of further intervention.
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Competition of interest: none.
The editors and reviewers of this article have no relevant financial relationships to disclose per the JVS policy that requires reviewers to decline review of any manuscript for which they may have a competition of interest.
PII: S0741-5214(10)02398-0
doi:10.1016/j.jvs.2010.09.068
http://www.jvascsurg.org/article/S0741-5214(10)02398-0/abstract
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Vascular access for hemodialysis in the elderly
Nicola Swindlehurst, MBBS, Andrew Swindlehurst, MBBS, Heather Lumgair, MBBS, Irene Rebollo Mesa, PhD, Nizam Mamode, MB FRCS, Roberto Cacciola, MBBS, MD, FRCS, Iain Macdougall, MBChB MD FRCP
Received 26 January 2010; accepted 28 September 2010. published online 10 January 2011.
At a mean follow-up of 25 months, death with a functioning conduit occurred at the same rate in both groups (56% and 54%),
http://www.jvascsurg.org/article/S0741-5214(10)02398-0/abstract
This study was done in the UK where fistula creation may have a higher success rate than the US. The statistics on 25 month mortality rate for both groups are terrible at more than 50%.