I Hate Dialysis Message Board
Dialysis Discussion => Dialysis: News Articles => Topic started by: greg10 on November 22, 2010, 08:23:30 PM
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http://www.nejm.org/doi/full/10.1056/NEJMoa1001593#t=abstract
Just- released findings of the Frequent Hemodialysis Network (FHN) Daily Trial that compared in-center hemodialysis administered under a three times per week schedule ("conventional dialysis") versus six shorter sessions per week ("short daily dialysis"). The FHN Daily Trial, published in the New England Journal of Medicine, was a landmark, randomized, controlled study sponsored by the National Institute for Diabetes and Digestive and Kidney Diseases (NIDDK) and the Centers for Medicare and Medicaid Services (CMS).
Frequent hemodialysis was associated with improved control of hypertension and hyperphosphatemia. There were no significant effects of frequent hemodialysis on cognitive performance, self-reported depression, serum albumin concentration, or use of erythropoiesis-stimulating agents.
In the chart below, LV mass is left ventricular mass. When a patient has adequate dialysis, he is more likely to have lower weight gain and therefore lesser chance of an enlarged LV mass.
"the lower weight gain between dialysis sessions in the frequent-hemodialysis group may be responsible for some of the benefit that we observed with respect to left ventricular mass. Although frequent hemodialysis is far from perfect, it may more closely approximate the capacity of a native or transplanted kidney to regulate extracellular volume and solute composition."