I Hate Dialysis Message Board
Dialysis Discussion => Dialysis: Transplant Discussion => Topic started by: karen547 on September 23, 2010, 03:07:57 AM
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I went into clinic monday and everything was fine until we looked at labs my creatnine went to 8 and they can't figure why. They did a biopsy and ultrasound which shows some damage but they know its not cellular rejection or a urine leak so I'm just waiting for them to figure out what type of rejection if any this is
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So sorry to read this Karen. I'm keeping everything crossed that they will be able to figure out what might be going on and reverse the rejection. :grouphug;
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Praying that they can help.... :cuddle;
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whoa!!!
Nasty surprise!!!!! :(
Try and stay positive - it could just be a more mild case of rejection, or even something else... did they re-do the test?? Hang in there... none of us will let up wishing the very best for you and your new gift!!!!
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:pray;
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Karen, don't panic, they will do their best to keep it working. Good luck
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:cuddle; I hope they can rescue the kidney - best wishes Karen.
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:grouphug;
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:cuddle;
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:grouphug;
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Gregory's kidney took quite a while to settle in for the long haul. Hoping your kidney will settle down soon. :grouphug;
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oh noooooo hang in there, maybe it's taking a little nap??? :cuddle; :cuddle;
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So sorry for this setback. I'll have you in my prayers. :pray;
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Praying for you!
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Oh damn I hope it is not going to be bad news. Hang in there things aren't always what they appear to be. I'm praying for you. :grouphug;
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I'm so sorry to hear this. You're in my thoughts and prayers. :pray; I hope they can reverse this quickly. :cuddle;
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:grouphug; :pray;
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Oh, KAren, I so hope not. Praying for you.
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Oh blimey. I have everything crossed for you. *hugs*
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Karen how do you feel? Other than scared and depressed. Do you feel sick? I hope and pray everything is OKAY.
:pray;
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I hope they find an answer quickly.Don't want you to lose that kidney.
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:grouphug;
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I logged in this morning expressly to see how you are going Karen. Any news? :pray;
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Fingers crossed for you! Hang in there.
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Praying that you and your kidney are ok,
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I'm sorry to be so uninformed, but I didn't realize there were different kinds of rejection. Could someone tell me more about this?
You are in my thoughts and prayers. I am hoping that all will be well. It must be an agonizing time for you. We are hear to help you in any way we can. :grouphug;
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Karen, I hate this for you. My team told me that they did my biopsy so early so they could get a jump on the rejection. I was told there are so many things they can do early on. Mine turned out to be a kidney that isn't wanting to wake up. I found out last week that the lady who got the twin to my kidney is having the same issue. Interesting. Anyway, I hope they can get a grip on this and turn it around. Try to rest, and keep drinking ( I have never had so much fluid in one day before!) Please let us know as soon as you find out anything. We are all worried and saying lots of prayers for you. :pray;
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I'm sorry to be so uninformed, but I didn't realize there were different kinds of rejection. Could someone tell me more about this?
Acute rejection
Acute rejection usually begins one week after transplantation (as opposed to hyperacute rejection, which is immediate). The risk of acute rejection is highest in the first three months after transplantation. However, acute rejection can also occur months to years after transplantation. A single episode of acute rejection is not a cause for concern if recognized and treated promptly, and rarely leads to organ failure. But recurrent episodes are associated with chronic rejection. Acute rejection occurs to some degree in all transplants (except those between identical twins). It is caused by mismatched HLA, which are present on all cells of the body. There are a large number of different alleles of each HLA, so a perfect match between all HLA in the donor tissue and the recipient's body is extremely rare. The diagnosis of acute rejection relies on clinical data, including patient signs and symptoms, laboratory testing and ultimately a tissue biopsy. The biopsy is interpreted by a pathologist who notes changes in the tissue that suggest rejection. Acute transplant rejection can be treated using chemotherapeutic drugs designed to suppress the immune system (see list below). Acute rejection is normally treated initially with a short course of high-dose corticosteroids, which is usually sufficient to treat successfully. If this is not enough, the course can be repeated or a triple therapy regimen can be used, consisting of a corticosteroid plus a calcineurin inhibitor and an anti-proliferative agent.
Chronic rejection
The term "chronic rejection" was initially a term used to describe a long-term loss of function in transplanted organs, associated with fibrosis of the internal blood vessels of the transplanted tissue. But this pathology is now termed chronic allograft vasculopathy. The term chronic rejection is reserved for cases of transplant rejection where the rejection is due to a poorly understood chronic inflammatory and immune response against the transplanted tissue. Chronic transplant rejection is irreversible and cannot be treated effectively. Treatments with inhaled cyclosporin are being investigated as a means to delay or prevent chronic rejection of the lungs. At present the only definitive treatment is re-transplantation, if patients can be re-allocated and if donors are available.
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Hey Karen, just hoping your ok, thinking about you x x
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I think everyone eventually will have one bout of rejection with a new kidney. My first was a year to the day after the transplant. I kept the kidney for 7 years after that. It was treated successfully twice for rejection. Don't lose hope! Some rejections are easily fixable.
Incidentally, I had a rejection episode of my last kidney about 2 years after I started dialysis. I didn't know that could happen, and it took them a few weeks to figure out why I was so sick. I think it was a learning experience for all involved
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I'm being discharged tomorrow well technically today since its like 230 am! I had atn which was caused possibly by the cipro given to me for the uti! I looked through my records which I know is frowned upon but was curious and apparently cipro causes kidney damage?! But the good news is that my creatnine is going down and I'm not gonna lose the kidney! I was in for ten days total so I'm ready to leave• I will let you all know more when I go to clinic monday• They are also giving me vitamin d and have me on valium for anxiety now• Thanks for the well wishes all!
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:2thumbsup; Glad to hear from you Karen! I bet you'll be happy to go home.
Best wishes for continued recovery! :cuddle;
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Great news! :thumbup; You just keep on keeping on, girl!
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O that's very good news.
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Thank goodness for that.You take care Karen.
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YAY!!! Super happy dance!!! It will be great for you to get home I'm sure!!!
:yahoo; :yahoo; :yahoo; :bandance;
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Thank Goodness!!! :clap;
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:bandance; :bandance;
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sooooooooo glad to hear your doing ok. :bandance; :bandance; :bandance; :bandance; :bandance;
look after yourself and take care x x :cuddle;
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Yay! That's great to hear! :2thumbsup;
I looked through my records which I know is frowned upon but was curious and apparently cipro causes kidney damage?!
Frowned upon to look through your own records? What's that about?
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Frowned upon to look through your own records? What's that about?
Oh, they hate if when you do that - they are afraid you might find out something useful, like what they have written down about your personality! You can request them, of course, but they still grouch if you look at them in the hospital.
Yay, Karen! Glad to hear things are improving!
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Excellent news, Karen! :clap;
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What a relief. You must have been so worried but now I hope you can heal quickly and get your creatinine where you want it.
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:clap; :clap; :clap;